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Moreover, metabolomics has identified distinctive changes in inflammatory markers and energy metabolism-related metabolites in individuals with depression, further supporting the potential of metabolomics as a valuable tool in depression research [398,399,400,401]

Most studies fail to include direct statistical comparisons between supplements or report long-term safety outcomes

In vitro study using human vascular endothelial cells further confirmed the increased mRNA and protein expressions of VEGFR2 but not VEGF-A by BPC 157

Female BALB/c mice, aged 68 weeks, were purchased from Kobay Experimental Animal Laboratory (Ankara, Turkey) and housed at 21 C temperature and 3070% humidity under a 12-h light and darkness cycle and regular autoclave chow diet with water